Luigi Serafini has exhibited at Palazzo Grassi, Venice (1981); Hayden Gallery, MIT, Cambridge (1983); Mudima Foundation, Milan (1998); XII Quadriennale of Rome (1999); Galleria Nazionale d’Arte Moderna, Rome (2001); Padiglione d’Arte Contemporanea, Milan (2007); Val Bregalia, Switzzerland (2007) and the 54th Venice Biennale (2011).